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Invitrogen™ Phospho-NBS1 (Ser278) Polyclonal Antibody

Descrizione
Antibody detects endogenous levels of p95/NBS1 only when phosphorylated at Sersine 278.
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
Specifica
Specifica
| Antigene | Phospho-NBS1 (Ser278) |
| Applicazioni | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classificazione | Polyclonal |
| Concentrazione | 1 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | NBN |
| N. accesso geni | O60934, Q9JIL9, Q9R207 |
| Alias gene | AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1 |
| Simboli geni | NBN |
| Vedi altri risultati |
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