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Invitrogen™ Phospho-SNAIL (Ser246) Polyclonal Antibody
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Codice prodotto. 16611165
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
16611165 100 μL 100µL
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Codice prodotto. 16611165 Fornitore Invitrogen™ N. del fornitore PA5104712

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Descrizione

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of SNAIL only when phosphorylated at Serine 246.

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Phospho-SNAIL (Ser246)
Applicazioni Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Snai1
N. accesso geni O95863, Q02085
Alias gene AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
Simboli geni Snai1
Specie ospite Rabbit
Immunogeno A synthesized peptide derived from human SNAI1(Accession O95863), corresponding to amino acid residues around phosphorylated Ser246.
Metodo di purificazione Sequential chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 116490, 20613, 6615
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Forma Liquid
Isotype IgG
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