missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Crosslinking, Labeling and Protein Modification
  5. Crosslinking Reagents
  6. Thermo Scientific™ Crosslinker Pierce™ EDC

Thermo Scientific™ Crosslinker Pierce™ EDC

Codice prodotto. 11851335 Sfoglia Tutto Thermo Scientific Prodotti
Cambia vista
Click to view available options
Quantità:
10 mg
10 x 1 mg
5 g
25 g
Dimensione della confezione:
10mg
25g
5g
pezzi 10
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Codice prodotto. Quantità unitSize
11851335 5 g 5g
15781819 10 x 1 mg pezzi 10
11844071 10 mg 10mg
11861335 25 g 25g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Codice prodotto. 11851335 Fornitore Thermo Scientific™ N. del fornitore 22980

Effettua il per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso!

223.25 EUR valido fino al 2026-04-30
MIGLIOR PREZZO in promozione! Usa il codice promo "28034" per avere il tuo prezzo promozionale.
This item is not returnable. View return policy

Description

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

Thermo Scientific™ Pierce EDC is a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation.

EDC is the abbreviation for 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, a crosslinker that has been used in diverse applications such as forming amide bonds in peptide synthesis, attaching haptens to carrier proteins to form immunogens, labeling nucleic acids through 5Æphosphate groups and creating amine-reactive NHS-esters of biomolecules. EDC reacts with a carboxyl to form an amine-reactive O-acylisourea intermediate. If this intermediate does not encounter an amine, it will hydrolyze and regenerate the carboxyl group. In the presence of N-hydroxysulfosuccinimide (Sulfo-NHS, Part No. 24510), EDC can be used to convert carboxyl groups to amine-reactive Sulfo-NHS esters.

Highlights:

  • Zero-length crosslinker
  • Numerous chemical conjugates can be synthesized via available –COOH and –NH2 groups
  • Amide bond formed provides a neutral linkage, which is ideal for preparing peptides and antigens
  • Adding Sulfo-NHS (Part No. 24510) enhances the coupling reaction at physiological pH conditions
  • Reactive groups: carbodiimide
  • Reactive toward: carboxyl and amino groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Carboxyl
Cleavable No
Descrizione EDC
Peso molecolare 191.7
PEGylated No
Lunghezza braccio spaziatore 0.0 Å
Content And Storage Upon receipt store desiccated at -20°C.
Permeabilità celle No
Shipping Condition Wet Ice
Linea di prodotti Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Carbodiimide
Spacer Short (<10 Å)
Forma Powder
Quantità 5 g
Solubilità Water
Formato Standard, Single-use, Premium-grade
Solubile in acqua Yes
Product Type Crosslinker
Show More Show Less

Safety and Handling

compliance-icons
Product Identifier
  • 1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE. HCl (EDC)
 Signal Word
  • Attenzione
 Hazard Category
  • Corrosione/irritazione della pelle Categoria 2
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
 Hazard Statement
  • H315-Provoca irritazione cutanea.
  • H319-Provoca grave irritazione oculare.
  • H335-Può irritare le vie respiratorie.
 Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.