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Thermo Scientific™ Idrossilammina·HCl Pierce™

Product Code. 11881405 Shop All Thermo Scientific Products
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Quantità:
25 g
Unit Size:
25g
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11881405 25 g 25g
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Product Code. 11881405 Supplier Thermo Scientific™ Supplier No. 26103

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Description

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, including to cleave Asn-Gly peptide bonds and to deprotect (expose) sulfhydryls for conjugation following modification with SATA and similar reagents.

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, which include cleaving Asn-Gly peptide bonds and deprotecting (exposing) sulfhydryls on SATA-modified molecules for conjugation. Hydroxylamine·HCl is a strong reducing agent that is useful in biochemical crosslinking applications, including the deacetylation of SATA and chemical cleavage of EGS and Sulfo-EGS. Hydroxylamine converts carbonyl compounds (aldehydes and ketones) to their oxime derivatives in the presence of a weak base. Therefore, crosslinkers and other compounds that contain a carbonyl within their structure are cleavable with hydroxylamine-HCl.

Highlights:

  • Exposes protected sulfhydryl groups on SATA-modified molecules
  • Cleaves carbonyl-containing crosslinkers such as EGS

Reagent Properties:

  • Chemical name: Hydroxylamine Hydrochloride
  • Chemical formula: NH2OH·HCl
  • Molecular weight: 69.49
  • CAS Number: 5470-11-1
  • Form: White crystals, free of foreign material
  • Solubility: 10%
TRUSTED_SUSTAINABILITY

Specifications

CAS 5470-11-1
Content And Storage Upon receipt store desiccated at room temperature. Product shipped at ambient temperature.
Linea di prodotti Pierce
Forma Solid
Tipo di reagente SATA
Quantità 25 g
Product Type Hydroxylamine Hydrochloride

Safety and Handling

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Product Identifier
  • Hydroxylamine Hydrochloride 25 Gm
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità acuta Categoria 3
  • Tossicità acuta Categoria 4
  • PERICOLO ACUTO PER L'AMBIENTE ACQUATICO Acuto 1
  • cancerogenicità Categoria 2
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Sostanze e miscele corrosive per i metalli Categoria 1
  • Corrosione/irritazione della pelle Categoria 2
  • Sensibilizzazione della pelle Categoria 1
  • Tossicità specifica per organi bersaglio (esposizione ripetuta) Categoria 2
 Hazard Statement
  • H290-Può essere corrosivo per i metalli.
  • H301-Tossico se ingerito.
  • H312-Nocivo per contatto con la pelle.
  • H315-Provoca irritazione cutanea.
  • H317-Può provocare una reazione allergica cutanea.
  • H319-Provoca grave irritazione oculare.
  • H351-Sospettato di provocare il cancro.
  • H373-Può provocare danni agli organi.
  • H400-Molto tossico per gli organismi acquatici.
 Precautionary Statement
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico/
  • P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
  • P390-Assorbire la fuoriuscita per evitare danni materiali.
  • P406-Conservare in recipiente resistente alla corrosione/ provvisto di rivestimento interno resistente.
  • P501b-Smaltire il prodotto/recipiente in conformità con le disposizioni locali/regionali/nazionali/internazionali.
 Supplemental information
  • MIXTURE LIST-Contain: Hydroxylamine, hydrochloride

For Research Use Only. Not for use in diagnostic procedures.

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