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Progesterone, 98%, Thermo Scientific Chemicals

Codice prodotto. 10368310 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Quantità:
5 g
25 g
100 g
Imballaggio:
Bottiglia in vetro
Dimensione della confezione:
100g
25g
5g
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Codice prodotto. Quantità Imballaggio Dimensione della confezione
10368310 5 g Bottiglia in vetro 5g
10328360 25 g Bottiglia in vetro 25g
10277303 100 g Bottiglia in vetro 100g
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Product Code. 10368310 Supplier Thermo Scientific Acros Supplier No. 225650050
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Description

Progesterone, CAS # 57-83-0, is a naturally occurring hormone required for maintenance of the uterine endothelium and suppression of estrogens.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Progesterone is a sex hormone required for suppression of estrogen signaling and is also involved in transcriptional activation

• Progesterone maintains the uterine endothelium and sustains pregnancy through suppression of muscle contractility

Applications

• Progesterone signaling is relevant to the study of breast cancer

Literature References

Kim, O.; Park, E.Y.; Kwon, S.Y.; Shin, S.; Emerson, R.E.; Shin, Y.H.; DeMayo, F.J.; Lydon, J.P.; Coffey, D.M.; Hawkins, S.M.; Quilliam, L.A.; Cheon, D.J.; Fernández, F.M.; Nephew, K.P.; Karpf, A.R.; Widschwendter, M.; Sood, A.K.; Bast, R.C. Jr.; Godwin, A.K.; Miller, K.D.; Cho, C.H.; Kim, J. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020, 117(50), 31993-32004.

Jain, V.; McDonald, S.D.; Mundle, W.R.; Farine, D. Guideline No. 398: Progesterone for Prevention of Spontaneous Preterm Birth. J Obstet Gynaecol Can. 2020, 42(6), 806-812.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 57-83-0
Formula molecolare C21H30O2
Molecular Weight (g/mol) 314.46
Numero MDL MFCD00003658
InChI Key RJKFOVLPORLFTN-LEKSSAKUSA-N
Sinonimo progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan
PubChem CID 5994
ChEBI CHEBI:17026
IUPAC Name (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

Specifications

Materiale o nome chimico Progesterone
Punto di fusione 126°C to 131°C
Colore Brown-Yellow to Yellow
Perdita all'essiccatura 0.5% max. (500 mg, 105°C, 2 hrs)
Spettro a infrarossi Authentic
Intervallo percentuale saggio 97.5% min. (HPLC)
Imballaggio Bottiglia in vetro
Quantità 5 g
Indice di Merck 15, 7889
Condizione di rotazione specifica +190° (20°C c=1,ethanol)
Rotazione specifica + 190
Informazioni di solubilità Solubility in water: insoluble. Other solubilities: soluble in alcohol,acetone,dioxane,conc. h2so4
Peso formulazione 314.46
Percent Purity 98%
Forma fisica Crystalline Powder, Crystals or Chunks
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Safety and Handling

compliance-icons
Product Identifier
  • Progesterone
 Signal Word
  • Attenzione
 Hazard Category
  • cancerogenicità Categoria 2
 Hazard Statement
  • H351-Sospettato di provocare il cancro.
 Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
SDS

RUO – Research Use Only

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