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Invitrogen™ Prosapip2 Polyclonal Antibody
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Codice prodotto. 12828992
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità Dimensione della confezione
12828992 100 μg 100µg
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Codice prodotto. 12828992 Fornitore Invitrogen™ N. del fornitore PA520814
  • ONLINE EXCLUSIVE PRICE
    530.00€
    450.50€ / 100µg
    Risparmia 79.50€
    15% Sconto
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Spedizione stimata: 15-09-2026
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Descrizione

Rabbit Polyclonal Antibody

A suggested positive control is rat liver tissue lysate. PA5-20814 can be used with blocking peptide PEP-0928.

Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappa-B pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Prosapip2
Applicazioni Immunohistochemistry, Western Blot
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.02% sodium azide
Gene TBKBP1
N. accesso geni A2A9T0, A7MCY6, Q6DG50
Alias gene 3110043L15Rik; KIAA0775; Prosapip2; Protein ProSAPiP2; RGD:631328}; Similar to NAP1 TBK1 adapter; Sintbad; TANK-binding kinase 1-binding protein 1; TBK1 binding protein 1; TBK1-binding protein 1; Tbkbp1; tbkbp1 {ECO:0000312
Simboli geni TBKBP1
Specie ospite Rabbit
Immunogeno A 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 266764, 73174, 9755
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Forma Liquid
Isotype IgG
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