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PROTAC ERα Degrader-2, MedChemExpress

Codice prodotto. 16474538
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Codice prodotto. 16474538 Fornitore Medchem Express N. del fornitore HY111846
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Spedizione stimata: 12-10-2026
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Beskrivning

MedChemExpress PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

Specifikationer

Materiale o nome chimico PROTAC ERα Degrader-2
CAS 1351169-29-3
Colore White
Note sul grado di purezza Research
Formula molecolare C42H61N5O8
Quantità 10 mg
Informazioni di solubilità DMSO : 200 mg/mL (261.79 mM; Need ultrasonic)
SMILES C[C@@]12[C@](CC/C2=N\OCC(NCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)=O)([H])[C@@]4([H])[C@](C5=CC=C(O)C=C5CC4)([H])CC1
Molecular Weight (g/mol) 763.96
Peso formulazione 763.96
Percent Purity 98.02%
Grado Research
Forma fisica Solid
Da utilizzare con (applicazione) Cancer-programmed cell death
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Research purposes only

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