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R&D Systems™ Quantikine Immunoassay Control 1137 for Human Serum TIM-1
Descrizione
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types, epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, glycoproteins of number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate phagocytosis, clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation, enhances Th2 cytokine production. TIM-1 serves as cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in urine during nephropathy.
- Storage: Store unopened product at 2 to 8°C. Do not use past expiration date.
Specifica
Specifica
| Content And Storage | Store the unopened product at 2°C to 8°C. Do not use past expiration date. |
| Tipo | Control Set for ELISA Kit |
| ID gene (immissione) | 26762 (Human); 171283 (Mouse); 286934 (Rat); 102141332 (Cynomolgus Monkey) |
| Intended Use | For quantitative measurement of T cell immunoglobulin protein levels |
| Nome del prodotto | Immunoassay Control Set 920 |
| Sorgente | Human |
| Gene bersaglio | T Cell Immunoglobulin Mucin-1 |
For Research Use Only
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