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VASP (phospho S238), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Descrizione
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq
Specifica
Specifica
| Antigene | VASP |
| Applicazioni | Immunohistochemistry (PFA fixed), Western Blot |
| Classificazione | Polyclonal |
| Concentrazione | 1 mg/mL |
| Coniugato | Unconjugated |
| Descrizione | Rabbit polyclonal antibody raised against synthetic phosphopeptide of VASP. |
| Diluizione | Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulazione | In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene | VASP |
| Simboli geni | VASP |
| Vedi altri risultati |
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