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RAF1 Mouse anti-Human, Mouse, Clone: 1D6A1, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66592-1-IG-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898605

  • 349.00€ / 150µL

Spedizione stimata: 19-12-2022
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Descrizione

Descrizione

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
Specifica

Specifica

RAF1
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P04049, Q99N57
RAF1
RAF1 Fusion Protein Ag25423
150 μL
Primary
Mouse, Human
Antibody
IgG2a
Western Blot, Immunohistochemistry (Paraffin)
1D6A1
Unconjugated
RAF1
c Raf, CRAF, NS5, Proto oncogene c RAF, RAF, Raf 1, RAF1
Mouse
Protein A
RUO
110157, 5894
-20°C
Liquid
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali