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Invitrogen™ RAP2A/RAP2B Monoclonal Antibody (455410)

Descrizione
Reconstitute at 0.5 mg/mL in sterile PBS.
RAP2A and RAP2B are genes encoding small GTPases that belong to the Ras-related protein family. These proteins are involved in various cellular processes, including cell proliferation, differentiation, and migration. RAP2A and RAP2B function as molecular switches, cycling between an active GTP-bound state and an inactive GDP-bound state, thereby regulating signal transduction pathways. They play crucial roles in the organization of the actin cytoskeleton, vesicle trafficking, and cell adhesion. RAP2A and RAP2B are implicated in the regulation of neuronal development and plasticity, and their dysregulation has been associated with neurological disorders. Additionally, abnormal expression or mutations in these genes have been linked to cancer progression, as they can influence tumor cell migration and invasion. Understanding the specific mechanisms and functions of RAP2A and RAP2B is important for elucidating their roles in both normal cellular physiology and disease states. As such, these genes are significant targets in research aimed at developing therapeutic interventions for cancer, neurodegenerative diseases, and other conditions involving cellular signaling abnormalities.
Specifica
Specifica
| Antigene | RAP2A/RAP2B |
| Applicazioni | Western Blot |
| Classificazione | Monoclonal |
| Clone | 455410 |
| Concentrazione | 0.5 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with trehalose and no preservative |
| Specie ospite | Mouse |
| Immunogeno | E. coli-derived recombinant human Rap2A/B, Met1-Gln183. |
| Metodo di purificazione | Protein A/G |
| Vedi altri risultati |
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