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enQuireBio™ Recombinant Mouse Leptin tA Protein
A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.
Marca: enQuireBio™ QP10764-5ug
Dettagli aggiuntivi : Peso : 0.01000kg
Specifica
| Leptin tA Protein | |
| Research Use Only | |
| Leptin Antagonist Triple Mutant Mouse Recombinant half-life in circulation after SC injection was over 20 hours. Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Mouse Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. | |
| Mouse | |
| Untagged | |
| Greater than 99.0% as determined by:(a) Gel filtration analysis. (b) Analysis by SDS-PAGE. |
| 5 μg | |
| < 1.0 EU per ug protein as determined by the LAL method. | |
| Recombinant Protein | |
| E. coli | |
| The Mouse Leptin triple antagonist was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3. |