Thermo Scientific™ Coagulase Plasma

Detect coagulase enzyme in staphylococci with Coagulase Plasma.

Detect coagulase enzyme in staphylococci with Thermo Scientific™ Remel™ Coagulase Plasma. The enzyme coagulase acts on a constituent of rabbit plasma to produce a thrombin-like substance which activates fibrinogen to form fibrin clot. In 1940, Fairbrother and Chapman et al. reported pathogenic staphylococci can be identified based on the ability to coagulate plasma.^1,2 Chapman found rabbit plasma to be superior to other types of plasma in terms of clotting activity.³ Bayliss and Hall recommended replacing the citrate anticoagulant with EDTA to avoid false-positive clots.⁴