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Rifabutin, 98%, Thermo Scientific Chemicals

Codice prodotto. 15731769 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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1 g
5 g
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1g
5g
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15731769 5 g 5g
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Codice prodotto. 15731769 Fornitore Thermo Scientific Acros N. del fornitore 461210050
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Beschreibung

Rifabutin, CAS # 72559-06-09, is a broad-spectrum antibiotic with activity against mycobacteria, gram-positive and gram-negative bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Rifabutin is a compound with antibacterial activity most commonly used against Mycobacterium tuberculosis
  • Rifabutin is a derivative of Rifamycin S that acts through blocking RNA polymerase subunit beta (RpoB)
  • Rifabutin is an inducer as well as a substrate of CYP3A, a cytochrome P450 enzyme

Applications

  • Rifabutin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
  • May be used in laboratory studies to determine drug resistance mutations present in Mycobacterium tuberculosis strains
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 72559-06-9
Formula molecolare C46H62N4O11
Molecular Weight (g/mol) 847.02
Numero MDL MFCD00866816
InChI Key ATEBXHFBFRCZMA-VXTBVIBXSA-N
Sinonimo rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427
PubChem CID 57448257
IUPAC Name (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1⁴,⁷.0⁵,³¹.0²⁶,³⁰]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
SMILES CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O

Spezifikation

Materiale o nome chimico Rifabutin
Intervallo percentuale saggio 97.5% min. (HPLC)
Quantità 5 g
Peso formulazione 847
Percent Purity 98%

RUO – Research Use Only

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