missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Signal Transduction Reagents and Kits
  6. Thermo Scientific Chemicals SB 225002

Thermo Scientific Chemicals SB 225002

Codice prodotto. 15496869
Cambia vista
Click to view available options
Quantità:
5 mg
10 mg
Dimensione della confezione:
10mg
5mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Codice prodotto. Quantità unitSize
15496869 10 mg 10mg
15486869 5 mg 5mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Codice prodotto. 15496869 Fornitore Thermo Scientific Chemicals N. del fornitore J65387.MA
Richiesta di formato massivo o personalizzato

Please to purchase this item. Need a web account? Register with us today!

Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

A potent, selective and competitive antagonist of the G-protein coupled receptor CXCR2

SB 225002 is a selective non-peptide CXCR2 inhibitor which suppresses IL-8 induced neutrophil chemotaxis and margination. In addition, SB 225002 reduces MPO activity, IL-1β, MIP-2, and keratinocyte-derived chemokine (KC) levels. Further studies suggest that SB 225002 decreases the expression of vascular endothelial growth factor, inducible NOS (NO synthase), and Cox-2 (cyclooxygenase-2 proteins) in colon tissue.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 182498-32-4
Formula molecolare C13H10BrN3O4, C13H10BrN3O4
Sinonimo 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea

Specifica

Quantità 10 mg
Descrizione Yellow
Content And Storage -30°C to -10°C
Da utilizzare con (applicazione) A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2
Peso formulazione 352.10g/mol
Sensibilità Moisture Sensitive
Solubilità Soluble to 100mM in DMSO and to 50mM in ethanol
Product Type Signal Transduction Reagent
Forma Solid
InChI Key MQBZVUNNWUIPMK-UHFFFAOYSA-N
SMILES OC1=C(NC(=O)NC2=CC=CC=C2Br)C=CC(=C1)[N+]([O-])=O
IUPAC Name 3-(2-bromophenyl)-1-(2-hydroxy-4-nitrophenyl)urea
Molecular Weight (g/mol) 352.14
Vedi altri risultati Mostra meno risultati

RUO – Research Use Only

Titolo del prodotto
Selezionare un problema

Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.