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SPHK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Specifica
Antigene | SPHK2 |
---|---|
Concentrazione | 0.27 mg/mL |
Applicazioni | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
Classificazione | Polyclonal |
Coniugato | Unconjugated |
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
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Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
16896934
|
Proteintech
17096-1-AP-20UL |
20 μL |
140.00€
20µL |
Spedizione stimata: 14-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
16886934
|
Proteintech
17096-1-AP-150UL |
150 μL |
399.00€
150µL |
Spedizione stimata: 14-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).Specifica
SPHK2 | |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q9JIA7, Q9NRA0 | |
308589, 56632, 56848 | |
SPHK2 Fusion Protein Ag10569 | |
Primary | |
-20°C | |
SPHK2 |
0.27 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
SK 2, sphingosine kinase 2, SPHK2, SPK 2 | |
Sphk2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |