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Thermo Scientific Chemicals Sulindac Sulfide

Catalog Number 15404559
209.34 EUR valido fino al 2024-03-29
Usa il codice promo "21615" per avere il tuo prezzo promozionale.


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Quantità:
100 mg
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price

 

It is also shown to inhibit growth and induce apoptosis in human prostate cancer cells through a COX-1 and COX-2 independent mechanism. Sulindac sulfide is an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of cyclooxygenase-2 in human colon cancer cells, and reduces tumor burden in adenomatous polyposis patients. Human endothelial cells, HMEC-1 were treated with Sulindac sulfide and the effect on cell survival was studies by MTT assay.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Quantità 100 mg
Descrizione Yellow
Da utilizzare con (applicazione) Active metabolite of sulindac; inhibits cyclooxygenase-1
CAS 32004-67-4
Formula molecolare C20H17FO2S, C20H17FO2S
Peso formulazione 340.41g/mol
Punto di fusione 189°C to 191°C
Solubilità Soluble in DMSO
Product Type Signal Transduction Reagent
Forma Powder
Numero MDL MFCD00869764
InChI Key LFWHFZJPXXOYNR-RQZCQDPDSA-N
SMILES CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1
IUPAC Name 2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid
Molecular Weight (g/mol) 340.41
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