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  5. Tocris Bioscience™ TC ASK 10

Tocris Bioscience™ TC ASK 10
GREENER_CHOICE

Codice prodotto. 30001618
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Quantità:
10 mg
50 mg
Dimensione della confezione:
10mg
50mg
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Codice prodotto. 30001618

Marca: Tocris Bioscience™ 4825/10

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Descrizione

Potent and selective ASK1 inhibitor; orally bioavailable

Potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 values are > 10 μM). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1005775-56-3
Formula molecolare C21H23Cl2N5O

Specifications

Materiale o nome chimico TC ASK 10
Quantità 10 mg
Peso formulazione 432.35
Purezza >98%
Peso molecolare 432.349
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