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Invitrogen™ TDG Polyclonal Antibody
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Codice prodotto. 13423267
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
13423267 100 μL 100µL
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Codice prodotto. 13423267 Fornitore Invitrogen™ N. del fornitore PA529140

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Descrizione

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, Jurkat, Raji, NCI-H929, TDG-transfected 293T. Predicted reactivity: Human (99%), Mouse (88%), Rat (87%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
TRUSTED_SUSTAINABILITY

Specifica

Antigene TDG
Applicazioni Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene TDG
N. accesso geni P56581, Q13569
Alias gene C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Simboli geni TDG
Specie ospite Rabbit
Immunogeno Recombinant protein encompassing a sequence within the center region of human TDG. The exact sequence is proprietary.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 21665, 6996
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Liquid
Isotype IgG
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