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TG 100801, MedChemExpress

Product Code. 16463618
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Quantità:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
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Product Code. 16463618

Brand: Medchem Express HY10186

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Description

MedChemExpress TG 100801 is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.

TG 100801 is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases

Specifications

Materiale o nome chimico TG 100801
CAS 867331-82-6
Colore Red
Note sul grado di purezza Research
Formula molecolare C33H30ClN5O3
Quantità 10 mg
Informazioni di solubilità DMSO : 5.56 mg/mL (9.58 mM; Need ultrasonic)
SMILES O=C(C1=CC=CC=C1)OC2=CC=C(Cl)C(C3=CC(C)=C(N=C(NC(C=C4)=CC=C4OCCN5CCCC5)N=N6)C6=C3)=C2
Molecular Weight (g/mol) 580.08
Peso formulazione 580.08
Percent Purity 95.0%
Grado Research
Forma fisica Solid
Da utilizzare con (applicazione) Cancer-Kinase/protease
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Research purposes only

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