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  5. Thermo Scientific™ TheraPure 2ʹ-Fluoro-iBu-G Phosphoramidite

Thermo Scientific™ TheraPure 2ʹ-Fluoro-iBu-G Phosphoramidite

Codice prodotto. 30054752 Sfoglia Tutto Thermo Scientific Prodotti
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Formato:
Amber Bottle (20-400 Thread)
Bottle (28-400 Thread)
Serum Vial Bottle
Dimensione della confezione:
0.25g
1g
500mg
Quantità:
0.25 g
0.5 g
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Codice prodotto. Formato Dimensione della confezione Quantità
30054752 Serum Vial Bottle 1g -
30054432 Amber Bottle (20-400 Thread) 0.25g 0.25 g
17927192 Bottle (28-400 Thread) 500mg 0.5 g
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Codice prodotto. 30054752 Fornitore Thermo Scientific™ N. del fornitore 27160702
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Spedizione stimata: 14-10-2026
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Descrizione

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in an amber bottle.

Available with a Serum Vial, 20-400 Finish, or 28-400 Finish neck style.

  • Serum vial neck style is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
  • 20-400 finish neck style is compatible with most Expedite synthesizers.
  • 28-400 finish neck style is compatible with most MerMade synthesizers.

Features:

  • Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula: C44H53FN7O8P
  • Base: G
  • Base Protection: iBu
  • Formula weight: 857.4 g/mol
  • CAS number: 144089-97-4
  • HPLC purity: >98%
  • 31P NMR purity: ≥98%
TRUSTED_SUSTAINABILITY

Specifica

Formato Serum Vial Bottle
Da utilizzare con (apparecchiatura) AKTA Synthesizers, Applied Biosystems Synthesizers
Product Type 2in-Fluoro-iBu-G CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Guanosine (G)
Reagent Features 2in-Fluoro modified
Shipping Condition Room Temperature
Purezza 98%
Tipo di reagente Phosphoramidite
Grado Standard
Nucleic Acid Type RNA
Forma Powder
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For Research Use Only.

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