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  5. Thermo Scientific™ TheraPure 2ʹ-OMe-iBu-G Phosphoramidite

Thermo Scientific™ TheraPure 2ʹ-OMe-iBu-G Phosphoramidite

Codice prodotto. 17967112 Sfoglia Tutto Thermo Scientific Prodotti
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1 g
Dimensione della confezione:
1g
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17967112 1 g 1g
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Codice prodotto. 17967112 Fornitore Thermo Scientific™ N. del fornitore 27204610
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Spedizione stimata: 16-10-2026
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Descrizione

2'-OMe-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in an amber bottle.

Available with a Serum Vial, 20-400 Finish, or 28-400 Finish neck style.

  • Serum vial neck style is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
  • 20-400 finish neck style is compatible with most Expedite synthesizers.
  • 28-400 finish neck style is compatible with most MerMade synthesizers.

Features:

  • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methyl-guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula—C45H56N7O9P
  • Base—G
  • Base Protection—iBu
  • Formula weight—869.9 g/mol
  • CAS number—150780-67-9
  • HPLC purity—≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
  • 31P NMR purity—>99%; Sum of non-primary peaks at 140-152 ppm ≤0.5%
TRUSTED_SUSTAINABILITY

Specifica

Da utilizzare con (apparecchiatura) Expedite Synthesizers
Product Type 2in-OMe-G CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Guanosine (G)
Reagent Features 2in-OMe modified
Shipping Condition Room Temperature
Purezza 99%
Quantità 1 g
Tipo di reagente Phosphoramidite
Grado TheraPure™
Nucleic Acid Type RNA
Product Line TheraPure
Forma Powder
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For Research Use Only.

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