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Thiamet G, Tocris Bioscience™

Catalog Number 18005142
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Quantità:
10 mg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Potent O-GlcNAcase inhibitor

Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Decreases the phosphorylation of tau protein in vivo. Promotes autophagy independently of mTOR pathway and reduces toxic protein species in mouse tauopathy model. Orally bioavailable and blood brain barrier permeable.
Materiale o nome chimico Thiamet G
CAS 1009816-48-1
Formula molecolare C9H16N2O4S
Quantità 10 mg
Sinonimo thiamet g
InChI Key PPAIMZHKIXDJRN-LQOSVEJXSA-N
SMILES CCNC1=NC2C(C(C(OC2S1)CO)O)O
IUPAC Name (3aS,5R,6R,7S,7aS)-2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
Molecular Weight (g/mol) 248.297
PubChem CID 122172999
Peso formulazione 248.3
Percent Purity >98%
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