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TLR1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19816-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899294

  • 121.38€ / 20µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

TLR1 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and co-expression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several tri-acylated lipopeptides. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for the TLR1 gene.
Specifica

Specifica

TLR1
Polyclonal
Unconjugated
TLR1
CD281, KIAA0012, rsc786, TIL, TLR1, toll like receptor 1
Rabbit
Antigen Affinity Chromatography
RUO
21897, 305354, 7096
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q15399, Q9EPQ1
TLR1
TLR1 Fusion Protein Ag13852
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali