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Triphosgene, 98%

Codice prodotto. 11452757
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Codice prodotto. 11452757 Fornitore Thermo Scientific Alfa Aesar N. del fornitore A14932.22
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CAS: 32315-10-9 | C3Cl6O3 | 296.73 g/mol

Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.

Solubility
Soluble in ether, ethanol, tetrahydrofuran, benzene, cyclohexane, chloroform, hexane, carbon tetrachloride, dichloromethane and chlorobenzene. Insoluble in water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 32315-10-9
Formula molecolare C3Cl6O3
Molecular Weight (g/mol) 296.73
Numero MDL MFCD00062848
InChI Key UCPYLLCMEDAXFR-UHFFFAOYSA-N
Sinonimo triphosgene, bis trichloromethyl carbonate, methanol, trichloro-, carbonate 2:1, ditrichloromethyl carbonate, triphosgene bis-trichloromethyl carbonate, methanol, 1,1,1-trichloro-, 1,1'-carbonate, triphosgen, tri phosgene, tri-phosgene
PubChem CID 94429
IUPAC Name bis(trichloromethyl) carbonate
SMILES C(=O)(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl

Specifications

Materiale o nome chimico Triphosgene
Punto di fusione 77°C to 91°C
Densità 1.6
Punti di ebollizione 203°C to 206°C
Quantità 100 g
Numero UN UN2928
Beilstein 1787583
Sensibilità Moisture sensitive
Informazioni di solubilità Soluble in ether,ethanol,tetrahydrofuran,benzene,cyclohexane,chloroform,hexane,carbon tetrachloride,dichloromethane and chlorobenzene. Insoluble in water.
Peso formulazione 296.75
Percent Purity 98%
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compliance-icons compliance-icons
Product Identifier
  • Triphosgene
Signal Word
  • Pericolo
Hazard Category
  • Tossicità acuta Categoria 2
  • Lesione oculare grave/irritazione oculare Categoria 1
  • Corrosione/irritazione della pelle Categoria 1B
Hazard Statement
  • H314-Provoca gravi ustioni cutanee e gravi lesioni oculari.
  • H318-Provoca gravi lesioni oculari.
  • H330-Letale se inalato.
Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P303+P361+P353-IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliere immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
  • P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
Supplemental information
  • MIXTURE LIST-Contain: Triphosgene

RUO – Research Use Only

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