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ZIP10 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA521064

Codice prodotto. 12829212

  • 558.00€ / 100µg

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Descrizione

Descrizione

A suggested positive control is human spleen tissue lysate. PA5-21064 can be used with blocking peptide PEP-1178.

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
TRUSTED_SUSTAINABILITY
Specifica

Specifica

ZIP10
Polyclonal
Unconjugated
SLC39A10
2900042E17Rik; 5430433I10; Kiaa1265; LZT-Hs2; mKIAA1265; Slc39a10; solute carrier family 39 (metal ion transporter), member 10; solute carrier family 39 (zinc transporter), member 10; solute carrier family 39 member 10; Zinc transporter ZIP10; ZIP10; ZIP-10; Zrt- and Irt-like protein 10
Rabbit
Antigen affinity chromatography
RUO
227059, 363229, 57181
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6P5F6, Q9ULF5
SLC39A10
An 18 amino acid peptide near the center of human ZIP10.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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