CAS RN 862507-23-1

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Ralimetinib dimesylate, MedChemExpress

MedChemExpress Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK α/β with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc.

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Specifiche

Peso formulazione	612.74
Sinonimo	LY2228820 dimesylate
Note sul grado di purezza	Research
Colore	Yellow
Forma fisica	Solid
Molecular Weight (g/mol)	612.74
Conservazione consigliata	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMILES	FC1=CC=C(C=C1)C2=C(NC(C(C)(C)C)=N2)C3=NC4=C(C=C3)N=C(N)N4CC(C)(C)C.OS(C)(=O)=O.OS(C)(=O)=O
Durata utile	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formula molecolare	C₂₆H₃₇FN₆O₆S₂
Percent Purity	96.97%
Informazioni di solubilità	DMSO : 61 mg/mL (99.55 mM; Need ultrasonic and warming)
CAS	862507-23-1
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	Ralimetinib dimesylate
Grado	Research

CAS RN 862507-23-1

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