CAS RN 944396-07-0

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NVP-BKM 120, TRC

CAS: 944396-07-0 Formula molecolare: C18H21F3N6O2 Molecular Weight (g/mol): 410.39 Sinonimo: BKM 120,5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine,NVP-BKM 120 IUPAC Name: 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine SMILES: Nc1cc(c(cn1)c2cc(nc(n2)N3CCOCC3)N4CCOCC4)C(F)(F)F

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Specifiche

Sinonimo	BKM 120,5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine,NVP-BKM 120
Formula molecolare	C18H21F3N6O2
CAS	944396-07-0
Molecular Weight (g/mol)	410.39
SMILES	Nc1cc(c(cn1)c2cc(nc(n2)N3CCOCC3)N4CCOCC4)C(F)(F)F
IUPAC Name	5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine

Buparlisib, MedChemExpress

MedChemExpress Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.

Prezzi e disponibilità
Specifiche

Peso formulazione	410.39
Sinonimo	BKM120 NVP-BKM120
Note sul grado di purezza	Research
Colore	Off-White
Forma fisica	Powder
Molecular Weight (g/mol)	410.39
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	FC(F)(C1=C(C2=CC(N3CCOCC3)=NC(N4CCOCC4)=N2)C=NC(N)=C1)F
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₁₈H₂₁F₃N₆O₂
Percent Purity	99.12%
Informazioni di solubilità	DMSO : ≥ 100 mg/mL (243.67 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
CAS	944396-07-0
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	Buparlisib
Grado	Research

CAS RN 944396-07-0

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