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Bioactive Small Molecules

Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1 – 15 di 1,532 risultati
1

Tocris Bioscience™ PEI STAR™ transfection reagent

Polyethylenimine (PEI) transfection reagent, chemically-defined

CAS 49553-93-7
Conservazione consigliata Store the unopened product at room temperature. Do not use past expiration date.
Materiale o nome chimico Poly[imino(1,2-ethanediyl)] hydrochloride
Bersaglio Transfection Reagent
4

SB 431542, Tocris Bioscience™

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Peso formulazione 384.39
Formula molecolare C22H16N4O3
CAS 301836-41-9
Conservazione consigliata Store at Room Temperature
5

Tocris Bioscience™ MLN 4924

Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable

Formula molecolare C21H25N5O4S
CAS 905579-51-3
Purezza 0.98
Conservazione consigliata Store at -20°C
Materiale o nome chimico [(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester
Bersaglio NEDD8 Activating Enzyme E1)
6

Tocris Bioscience™ PAG 4'-piperazine-4-methylpiperidine

Cereblon ligand with terminal piperidine for onward chemistry

7

Tocris Bioscience™ dTAG-47-NEG

Negative control for dTAG-47 (Cat. No. 7530)

8

Tocris Bioscience™ TH 9619 disodium salt

MTHFD2 inhibitor

Formula molecolare C17H16FN7Na2O7
Purezza 0.98
Conservazione consigliata Store at -20°C
Materiale o nome chimico Disodium N-[[5-[[2-(2,4-Diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)acetyl]amino]-3-fluoro-2-pyridinyl]carbonyl]-L-glutamate
Bersaglio Dehydrogenase Inhibitors
9

Tocris Bioscience™ SET 2

Selective TRPV2 antagonist

Formula molecolare C17H21F3N4O2S
CAS 2313525-20-9
Purezza 0.98
Conservazione consigliata Store at -20°C
Materiale o nome chimico N-(2-Furanylmethyl)-3-[[4-(methylpropylamino)-6-(trifluoromethyl)-2-pyrimidinyl]thio]propanamide
Bersaglio TRPV Antagonists
10

Tocris Bioscience™ CHDI 00484077

Potent and selective HDAC class IIa inhibitor

11

Tocris Bioscience™ DMNB-caged-Serine

Caged serine; excited by visible blue light

12

Tocris Bioscience™ CB 13

Potent dual CB1/CB2 agonist

Formula molecolare C26H24O2
CAS 432047-72-8
Purezza 0.99
Conservazione consigliata Store at Room Temperature
Materiale o nome chimico 1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone
Bersaglio Non-selective Cannabinoid Receptor Agonists
13

Tocris Bioscience™ Phototrexate

Photoswitchable inhibitor of human dihydrofolate reductase

14

Tocris Bioscience™ HER2 PROTAC™ CH7C4

Potent and selective HER2 targeting PROTAC™

15

Tocris Bioscience™ MSA 2

Non-nucleotide STING agonist; orally bioavailable

Formula molecolare C14H14O5S
CAS 129425-81-6
Purezza 0.98
Conservazione consigliata Store at -20°C
Materiale o nome chimico 4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid
Bersaglio STING Agonists