CAS RN 1627494-13-6

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AZD 8186, TRC

CAS: 1627494-13-6 Formula molecolare: C24H25F2N3O4 Molecular Weight (g/mol): 457.48 Sinonimo: AZD 8186,8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide IUPAC Name: 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide SMILES: C[C@@H](Nc1cc(F)cc(F)c1)c2cc(cc3C(=O)C=C(Oc23)N4CCOCC4)C(=O)N(C)C

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Specifiche

Sinonimo	AZD 8186,8-[(1R)-1-[(3,5-Difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide
Formula molecolare	C24H25F2N3O4
CAS	1627494-13-6
Molecular Weight (g/mol)	457.48
SMILES	C[C@@H](Nc1cc(F)cc(F)c1)c2cc(cc3C(=O)C=C(Oc23)N4CCOCC4)C(=O)N(C)C
IUPAC Name	8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide

AZD8186, MedChemExpress

MedChemExpress AZD8186 is a PI3K inhibitor, which potently inhibits PI3Kβ (IC50=4 nM) and PI3Kδ (IC5050=12 nM) with selectivity over PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM).

Prezzi e disponibilità
Specifiche

Peso formulazione	457.47
Note sul grado di purezza	Research
Colore	Off-White
Forma fisica	Powder
Molecular Weight (g/mol)	457.47
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	O=C(C1=CC([C@H](NC2=CC(F)=CC(F)=C2)C)=C3C(C(C=C(N4CCOCC4)O3)=O)=C1)N(C)C
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₂₄H₂₅F₂N₃O₄
Percent Purity	99.67%
Informazioni di solubilità	DMSO : ≥ 35 mg/mL (76.51 mM)
CAS	1627494-13-6
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	AZD8186
Grado	Research

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