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Thermo Scientific™ TheraPure™ 2'-Fluoro-Ac-C Phosphoramidite, 20-400 finish bottle
2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis.
Marca: Thermo Scientific™ 27-1604-09
Dettagli aggiuntivi : Peso : 0.04120kg
Descrizione
2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.
Specifica
| ≥98% | |
| Expedite Synthesizers | |
| 789.8 g/mol | |
| Store in freezer (at or below -20°C). | |
| 2in-Fluoro modified, Fast deprotection | |
| >98% (HPLC) | |
| Phosphoramidite | |
| RNA | |
| Oligonucleotide synthesis | |
| 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-fluorocytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | |
| 159414-99-0 |
| Amber bottle (20-400 finish neck style) | |
| Base: C Base Protection: Ac |
|
| 2in-Fluoro-Ac-C CEP | |
| Cytidine (C) | |
| Room Temperature | |
| 0.25 g | |
| TheraPure™ | |
| TheraPure™ | |
| Powder | |
| C41H49N5FO8P |
For Research Use Only. Not for use in diagnostic procedures.