missing translation for 'onlineSavingsMsg'
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Invitrogen™ 4EBP1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA528947
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Descrizione
Recommended positive controls: HeLa, H1299, HCT116, NB4, HL60. Predicted reactivity: Mouse (90%), Rat (92%), Pig (90%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Specifica
| 4EBP1 | |
| Polyclonal | |
| Unconjugated | |
| EIF4EBP1 | |
| 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 116636, 1978 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q13541, Q62622 | |
| EIF4EBP1 | |
| Full length human 4E-BP1 Recombinant protein. | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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