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Bcl-X Mouse, Unlabeled, Clone: 4, BD
Mouse Monoclonal Antibody
Specifica
| Antigene | Bcl-X |
|---|---|
| Clone | 4 |
| Concentrazione | 250μg/mL |
| Applicazioni | Western Blot |
| Classificazione | Monoclonal |
Descrizione
Bcl-x is related to the Bcl-2 protein and can function independently of Bcl-2 in regulating apoptosis (programmed cell death). The bcl-x transcript is found in a number of tissues, with the highest levels in the lymphoid and central nervous systems. Two distinct cDNA species, bcl-xL and bcl-xS, have been observed and appear to arise from alternate 5′ splice sites located within the first coding exon of the bcl-x gene. Bcl-xL is composed of 233 amino acids and is similar in size and structure to Bcl-2. Bcl-xS lacks 63 amino acids corresponding to the region of Bcl-xL with the highest degree of homology to Bcl-2. Like Bcl-2, Bcl-xL has been reported to inhibit cell death upon growth factor withdrawal in an IL-3-dependent cell line. However, Bcl-xS inhibits the ability of Bcl-2 to enhance cell survival in the absence of growth factors.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifica
| Bcl-X | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2b | |
| Affinity Purified |
| 4 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Chicken, Mouse, Rat | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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