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caveolin 1, caveolae protein, 22kDa, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against a full-length human CAV1 protein.
Marca: Abnova H00000857-D01P.100ug
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Descrizione
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEISpecifica
| caveolin 1, caveolae protein, 22kDa | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against a full-length human CAV1 protein. | |
| CAV1 | |
| BSCL3/CAV/CGL3/MSTP085/VIP21 | |
| Rabbit | |
| Affinity Purified | |
| RUO | |
| 857 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG |
| Western Blot | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_001753.3 | |
| CAV1 | |
| CAV1 (AAH82246.1, 1 a.a. ∼ 178 a.a) full-length human protein. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody |
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