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CD41b Mouse anti-Human, Unlabeled, Clone: HIP2, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 555468
Codice prodotto. 15808198
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133.00€
132.68€ / Pezzo
Risparmia 0.32€
0.24% Sconto
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Descrizione
The HIP2 monoclonal antibody specifically binds to CD41b. CD41b/CD41 is encoded by the ITGA2B gene and is also known as Platelet glycoprotein GPIIb and Integrin alpha IIb. CD41 is transmembrane glycoprotein that is post-translationally processed into a disulfide linked α-chain and β-chain. CD41 combines with CD61, otherwise known as Glycoprotein IIIa or β3 integrin, to form the CD41/CD61 (GPIIb/IIIa) complex. This complex is expressed on platelets and megakaryocytes and is involved in platelet activation, aggregation and binding to extracellular matrix proteins. Upon platelet activation, the CD41/CD61 complex can function as a receptor for fribrinogen, fibronectin and von Willebrand factor. In contrast to other CD41b antibodies, HIP2 does not detect anti-ZWa bound to GPIIb/IIIa. This antibody appears to be a weak aggregation inducer.
Specifica
| CD41b | |
| Monoclonal | |
| 0.5mg/mL | |
| ITGA2B; CD41; GP2B; GPIIb; GPalpha IIb; Platelet glycoprotein GPIIb | |
| Mouse | |
| 0.1 mg | |
| Immunology | |
| Human | |
| IgG3 κ |
| Flow Cytometry | |
| HIP2 | |
| Unconjugated | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
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Titolo del prodotto
For Research Use Only.
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