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MAD2 Mouse, Unlabeled, Clone: 48, BD

Mouse Monoclonal Antibody

255.73€ - 410.88€

Specifica

Antigene MAD2
Clone 48
Concentrazione 250μg/mL
Applicazioni Western Blot
Classificazione Monoclonal
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
15865579
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BD Biosciences
610678 		50 μg
ONLINE EXCLUSIVE PRICE
256.00€
255.73€ / 1 set
Risparmia 0.27€
0.11% Sconto
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15875579
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BD Biosciences
610679 		150 μg
ONLINE EXCLUSIVE PRICE
411.00€
410.88€ / 1 set
Risparmia 0.12€
0.03% Sconto
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Description

Description

Progression of the mammalian cell cycle is regulated by phosphorylation/dephosphorylation and synthesis/degradation of many key proteins. These events are of utmost importance at the checkpoints, or transition points, of the cell cycle. MAD2 (Mitotic Arrest Deficient) is the human homolog of a yeast and Xenopus protein that is essential for spindle assembly during mitosis. The human hsMAD2 gene encodes a protein of 205 amino acids with a predicted molecular weight of 23.5 kDa. Binding of affinity purified polyclonal antibodies to the MAD2 protein prevents mitosis of HeLa cells. This indicates that, like its invertebrate relatives, MAD2 is necessary for mitosis. Furthermore, MAD2 is localized at the kinetochore of condensed chromosomes during mitosis and cells defective in the mitotic checkpoint have reduced levels of MAD2.

Specifications

Specifications

MAD2
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2a
Affinity Purified
Mitotic Arrest Deficient-2
48
Western Blot
Unconjugated
RUO
Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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