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NAT1 Mouse, Unlabeled, Clone: 35, BD
Mouse Monoclonal Antibody
252.52€
Specifica
| Antigene | NAT1 |
|---|---|
| Clone | 35 |
| Concentrazione | 250μg/mL |
| Applicazioni | Immunofluorescence, Western Blot |
| Classificazione | Monoclonal |
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|---|---|---|---|---|---|---|---|---|---|
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
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15845619
|
BD Biosciences
610742 |
50 μg |
 253.00€ 252.52€ / 1 set Risparmia 0.48€ 0.19% Sconto |
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Descrizione
eIF-4 proteins are required for recognition of mRNA and acceleration of protein translation. This group of proteins consists of the RNA helicase eIF-4A, the RNA-binding protein eIF-4B, the cap-binding protein eIF-4E, and eIF-4G (p220). NAT1 (Novel APOBEC-1 Target no. 1), also known as DAP-5 (Death Associated Protein -5), is homologous to eIF-4G. Amino acid sequence comparison of NAT1 and eIF-4 shows that NAT1 lacks an eIF-4G N-terminal region. This region mediates eIF-4G association with eIF-4E. The highest degree of homology is
within the central portions of NAT1 and eIF-4G, while the lowest degree of homology occurs at the C-terminus. NAT1 more closely resembles a cleaved form of eIF-4G that is involved in cap-independent translation. It is thought that NAT1 is involved in the repression of translation via its inhibition of both cap-dependent and cap-independent translation.
Immunofluorescence, Immunoprecipitation, Western Blotting
Specifica
| NAT1 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified | |
| Novel APOBEC-1 Target no. 1; DAP-5; Death Associated Protein -5 |
| 35 | |
| Immunofluorescence, Western Blot | |
| Unconjugated | |
| RUO | |
| Bovine, Canine, Human, Mouse, Rat | |
| Human NAT1 aa. 672-830 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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