Learn More
Rab5 Mouse, Unlabeled, Clone: 1, BD
Mouse Monoclonal Antibody
225.77€ - 488.99€
Specifica
| Antigene | Rab5 |
|---|---|
| Clone | 1 |
| Concentrazione | 250μg/mL |
| Applicazioni | Western Blot |
| Classificazione | Monoclonal |
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|---|---|---|---|---|---|---|---|---|---|
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|
15865609
|
BD Biosciences
610724 |
50 μg |
226.00€ 225.77€ / 1 set Risparmia 0.23€ 0.10% Sconto |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | |||||
|
15875609
|
BD Biosciences
610725 |
150 μg |
489.00€ 488.99€ / 1 set Risparmia 0.01€ 0.00% Sconto |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | |||||
Descrizione
Rab5 is a low molecular weight GTP-binding protein that plays a role in endocytic vesicle traffic. Like other Rab proteins, Rab5 has C-terminal cysteine residues that are post translationally modified by geranylgeranylation which is critical for its membrane targeting. Rab5 is associated with early endosome and plasma membranes and evidence suggests that Rab5 regulates early endosome fusion. The GTP/GDP cycle controls shuttling of Rab proteins between the cytosol and membranes. In vitro, Rab5 proteins are removed from membranes by a GDP dissociation inhibitor protein (rabGDI) which leads to the formation of a cytosolic Rab5-rabGDI complex. Rab5 may insert into membranes by a multistep process in a which a transient GDP-Rab5 intermediate is formed and converted into GTP-Rab5 that subsequently enters the acceptor membrane and releases rabGDI into the cytosol.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifica
| Rab5 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2a | |
| Affinity Purified |
| 1 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human | |
| Human Rab5 aa. 1-215 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
Fornite il vostro feedback sul contenuto del prodotto compilando il modulo sottostante.