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Rab8 Mouse, Unlabeled, Clone: 4, BD

Mouse Monoclonal Antibody

180.83€

Specifica

Antigene Rab8
Clone 4
Concentrazione 250μg/mL
Applicazioni Western Blot
Classificazione Monoclonal
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Prodotti 1
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
15855669
Vedere i documenti
BD Biosciences
610844
50 μg
ONLINE EXCLUSIVE PRICE
181.00€
180.83€ / 1 set
Risparmia 0.17€
0.09% Sconto
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Beschreibung

Beschreibung

The members of the Ras superfamily of GTPases, which now includes more than 50 different proteins, shuttle between the GDP-bound inactive position and the GTP-bound active state. The GTPase activity of the Ras-like proteins is regulated by effectors that promote either the GDP- or the GTP-bound states. GTPases of the Ras superfamily have a role in controlling numerous events such as cell proliferation, nucleocytoplasmic transport, and vesicular traffic. The Rab superfamily of proteins includes more than 30 different members that are involved in the regulation of different steps of vesicular traffic. Subcellular localization and specific cellular function of each Rab appears to be encoded in the unique C terminal part of the proteins, known as the hypervariable region. The 207 amino acid Rab8 protein is closely related to the yeast Sec4p and regulates vesicle transport from the Trans-golgi Network to the basolateral plasma membrane in epithelial cells. In addition, Rab8 interacts with the stress-activated kinase rab8p, a close homologue of the GC Kinase. This interaction was found to be dependent on GTP.

Immunofluorescence, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

Rab8
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2b
Affinity Purified
4
Western Blot
Unconjugated
RUO
Canine, Drosophila, Human, Mouse, Rat
Human Rab8 aa. 84-205
Primary
Store undiluted at -20°C.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate

For Research Use Only.

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