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Rap1 Mouse, Unlabeled, Clone: 3, BD

Mouse Monoclonal Antibody

252.52€ - 454.75€

Specifica

Antigene Rap1
Clone 3
Concentrazione 250μg/mL
Applicazioni Western Blot
Classificazione Monoclonal
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
15805329
Vedere i documenti
BD Biosciences
610195
50 μg
ONLINE EXCLUSIVE PRICE
253.00€
252.52€ / 1 set
Risparmia 0.48€
0.19% Sconto
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15815329
Vedere i documenti
BD Biosciences
610196
150 μg
ONLINE EXCLUSIVE PRICE
455.00€
454.75€ / 1 set
Risparmia 0.25€
0.06% Sconto
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Descrizione

Descrizione

Rap1 is a member of the large Ras superfamily of low molecular weight GTP/GDP binding proteins. Like Ras, the Rap proteins cycle between a GDP-bound inactive form and a GTP-bound active form. Since Ras and Rap have the same amino acid sequence in their putativeeffector domain (aa. 32-40), it seems likely that they perform either similar or antagonistic functions. Rap1A and Rap1B are highly homologous proteins, differing in only 9 of their 184 amino acids. Overexpression of Rap1A (also known as Krev-1) causes reversion of the phenotype of a Ki-Ras-transformed cell line. In vitro, Rap1 can compete efficiently with p21ras for interaction with Ras-GAP. Though they appear to have similar activities, Rap1 and Ras differ in their cellular localization. Ras is found on the inner surface of the plasma membrane while Rap1 is associated with the Golgi.

This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifica

Specifica

Rap1
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
3
Western Blot
Unconjugated
RUO
Chicken, Frog, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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