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TRA-1-60 Mouse anti-Human, PE, Clone: TRA-1-60, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 560193
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Descrizione
The TRA-1-60 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-60 antigen is a sialylated epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-81, GCTM2, K4, and K21. The expression of TRA-1-60 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. TRA-1-60 antigen is released into the serum of patients bearing testicular tumors containing EC cells. As human EC and ES cells undergo differentiation, expression of TRA-1-60 antigen is lost.
Host Species: Mouse
Clone: TRA-1-60
Isotype: IgM, κ
Species Reactivity: Human
Immunogen: Human Embryonal Carcinoma Cell Line
Flow Cytometry
Specifica
| TRA-1-60 | |
| Monoclonal | |
| PE | |
| Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
| Human Embryonal Carcinoma Cell Line | |
| 100 Tests | |
| Cell Biology | |
| Human, Rhesus Monkey | |
| IgM κ |
| Flow Cytometry | |
| TRA-1-60 | |
| TRA-1-60(R) | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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