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API-1, Tocris Bioscience™
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Codice prodotto. 18015342
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Quantità:
10 mg
Dimensione della confezione:
10mg
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Codice prodotto. 18015342

Marca: Tocris Bioscience 3897/10

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Descrizione

Selective Akt/PKB inhibitor. Antitumor

Akt/protein kinase B (PKB) inhibitor. Binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation. Inhibits EGF-induced kinase activity of Akt1, Akt2 and Akt3. Induces cell growth arrest and apoptosis in human cancer cells expressing constitutively active Akt. Displays antitumor activity in vitro and in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico API-1
CAS 36707-00-3
Formula molecolare C13H15N5O6
Quantità 10 mg
Sinonimo api-1, 4-amino-8-3,4-dihydroxy-5-hydroxymethyl oxolan-2-yl-5-oxo, 4-amino-5,8-dihydro-5-oxo-8-?-d-ribofuranosyl-pyrido 2,3-d pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-beta-d-ribofuranosyl-pyrido 2,3-d pyrimidine-6-carboxamide, 4-amino-8-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl oxolan-2-yl-5-oxopyrido 2,3-d pyrimidine-6-carboxamide
InChI Key SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES C1=C(C(=O)C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)C(=O)N
IUPAC Name 4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
Molecular Weight (g/mol) 337.292
PubChem CID 24773090
Peso formulazione 337.29
Percent Purity >96%
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