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beta-Catenin Antibody (6F9), Alexa Fluor™ 350, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-54543AF350
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Descrizione
beta-Catenin Monoclonal specifically detects beta-Catenin in Human, Bovine, Canine, Chicken samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Specifica
| beta-Catenin | |
| Monoclonal | |
| Alexa Fluor 350 | |
| 50 mM sodium borate with 0.05% sodium azide | |
| CTNNB1 | |
| Recombinant chicken beta-Catenin (Uniprot: P35222) | |
| 0.1 mL | |
| Primary | |
| This monoclonal antibody recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC. | |
| Store at 4°C in the dark. |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| 6F9 | |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin | |
| beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923 | |
| Mouse | |
| Protein A or G purified | |
| Cancer, Cellular Markers, Cytoskeleton Markers, Extracellular Matrix, Immune System Diseases, Mucosal Immunology, Neuroscience, Phospho Specific, Signal Transduction, Stem Cell Signaling Pathway, Wnt Signaling Pathway | |
| 1499.0 | |
| Human, Bovine, Canine, Chicken | |
| IgG1 κ |
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