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CBX4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA512200

Dettagli aggiuntivi : Peso : 0.01000kg

Codice prodotto. 10018929

  • 473.00€ / 100µg
Spedizione stimata: 26-06-2024
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Descrizione

Descrizione

This antibody is predicted to react with mouse based on sequence homology.

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Specifica

Specifica

CBX4
Polyclonal
PBS with 0.09% sodium azide
O00257
CBX4
KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human CBX4
400 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
CBX4
Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog
Rabbit
Antigen affinity chromatography, Protein A
RUO
8535
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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