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CBX4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA512200
347.20 EUR valido fino al 2025-02-13
Usa il codice promo "24070" per avere il tuo prezzo promozionale.
338.68 EUR valido fino al 2025-03-29
Usa il codice promo "24111" per avere il tuo prezzo promozionale.
Allerta:
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price
Descrizione
This antibody is predicted to react with mouse based on sequence homology.
Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Specifica
| CBX4 | |
| Polyclonal | |
| PBS with 0.09% sodium azide | |
| O00257 | |
| CBX4 | |
| KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human CBX4 | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| CBX4 | |
| Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 8535 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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