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CD206 Mouse anti-Human, FITC, Clone: 15-2, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech FITC-65155-100TESTS
Descrizione
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
Specifica
| CD206 | |
| Monoclonal | |
| 4 μL/Test | |
| Mouse | |
| Primary | |
| Human, Mouse | |
| IgG1 κ |
| Flow Cytometry | |
| 15-2 | |
| FITC | |
| 100 Tests | |
| 4360 | |
| Liquid |
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