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CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), NovaFluor™ Yellow 700, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Marca: Invitrogen M036T02Y06
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Descrizione
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifica
| CD274 (PD-L1, B7-H1) | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| Q9EP73 | |
| Cd274 | |
| Affinity chromatography | |
| RUO | |
| 60533 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| MIH5 | |
| NovaFluor Yellow 700 | |
| Cd274 | |
| A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 | |
| Rat | |
| 25 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a λ |
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