Learn More
Gibco™ CTS™ (Cell Therapy Systems) Dynabeads™ CD3/CD28
Descrizione
CTS™ Dynabeads™ CD3/CD28 are intended for ex vivo isolation, activation, and expansion of human T-cells in translational research. The technology—previously known as Xcyte™ Dynabeads™ or Dynabeads™ ClinExVivo™ CD3/CD28—has been used in a number of clinical studies. By combining anti-CD3 and anti-CD28 antibodies on Dynabeads, the beads provide both the primary and co-stimulatory signals that are required for activation and expansion of T cells. CTS Dynabeads CD3/CD28 are manufactured and controlled according to ISO 9001:2000 and ISO 13485:2012 requirements. A Device Master File is held with the FDA for cross-referencing in IND applications, and a CoA is available on request. In the US, CTS Dynabeads CD3/CD28 are available for clinical use only under an approved Investigational New Drug (IND) application. Dynabeads™ Human T-Expander CD3/CD28 (Cat. No. 11141D) is the research grade version of CTS Dynabeads CD3/CD28, containing the same amount and ratio of antibodies from the same clones as CTS Dynabeads CD3/CD28, and intended for small scale pre-clinical research.
Applications:
The CTS Dynabeads CD3/CD28 technology has been successfully used in ex vivo isolation, activation, and expansion of T-cells in a number of studies, including studies on HIV infection and cancer. Other potential applications for this novel technology include research into treatment of autoimmune and infectious diseases and prevention of complications associated with chemotherapy and allogeneic stem cell transplantation.
Specifica
Specifica
| Tipo di cellula | T Cells (Whole Population) |
| Clonality | Monoclonal |
| Content And Storage | The product contains: CTS Dynabeads CD3/CD28 supplied as a sterile, non-pyrogenic suspension containing 4 x 108 Dynabeads/mL in phosphate buffered saline (PBS), pH 7.4, with 0.1% recombinant human serum albumin (rHSA). Store at: 2-8°C. |
| Product Type | Antibody Coated Bead |
| Tipo di prodotto finale | Cells |
| Linea di prodotti | CTS, DYNAL, Dynabeads |
| Quantità | 10 mL |
| Reattività | Human |
| Tipo di campione | Cell Cultures, Clinical Sample, PBMC |
| Shipping Condition | Wet Ice |
| Vedi altri risultati |
For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.
Fornite il vostro feedback sul contenuto del prodotto compilando il modulo sottostante.