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Invitrogen™ CYR61 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA5102355

Codice prodotto. 16698824

  • 493.00€ / 100µL

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Descrizione

Descrizione

Antibody detects endogenous levels of total CYR61/CCN1.

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
TRUSTED_SUSTAINABILITY
Specifica

Specifica

CYR61
Polyclonal
Unconjugated
CCN1
3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Rabbit
Affinity chromatography
RUO
16007, 3491, 83476
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O00622, P18406, Q9ES72
CCN1
A synthesized peptide derived from human CYR61(Accession O00622), corresponding to amino acid residues I199-T249.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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