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Dexamethasone 21-phosphate disodium salt, 98%, Thermo Scientific™

Dexamethasone 21-phosphate disodium salt, CAS # 2392-39-4, is a synthetic adrenal glucocorticoid with potent anti-inflammatory activity.

114.00€ - 344.00€

Identificatori chimici

CAS 2392-39-4
Formula molecolare C22H28FNa2O8P
Molecular Weight (g/mol) 516.41
Numero MDL MFCD00079105
InChI Key PLCQGRYPOISRTQ-FCJDYXGNSA-L
Sinonimo dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
PubChem CID 16961
ChEBI CHEBI:4462
IUPAC Name disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
15466189
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Thermo Scientific Alfa Aesar
J64083.03
1g
114.00€
1g
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15476189
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Thermo Scientific Alfa Aesar
J64083.06
5g
344.00€
5g
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Descrizione

Descrizione

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
Dexamethasone 21-phosphate disodium salt is a sodium phosphate salt form of dexamethasone, considered to be a synthetic adrenal glucocorticoid with anti-inflammatory activity
Application
Dexamethasone 21-phosphate disodium salt binds to specific nuclear steroid receptors, interfering with NF-kB activation and apoptotic pathways
It acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter
It has been used as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 in the induced reactivation and spontaneous shedding rabbit models
This compound is used to study its protective effects against cisplatin-induced ototoxicity in the inner ear of guinea pigs
Specifica

Identificatori chimici

2392-39-4
516.41
PLCQGRYPOISRTQ-FCJDYXGNSA-L
16961
disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
C22H28FNa2O8P
MFCD00079105
dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
CHEBI:4462
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]

Specifica

Dexamethasone 21-phosphate disodium salt
C22H28FNa2O8P
6473066
dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron
PLCQGRYPOISRTQ-FCJDYXGNSA-L
disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
16961
516.4
2392-39-4
MFCD00079105
142943
Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
516.41
CHEBI:4462
98%
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Sicurezza e movimentazione

Sicurezza e movimentazione

Harmful if swallowed, Suspected of damaging the unborn child, May cause damage to organs through prolonged or repeated exposure

Acute toxicity (category 4), Reproductive toxicity (category 2), Specific target organ toxicity after repeated exposure (category 2)

missing translation for 'einecsNumber' : 219-243-0

missing translation for 'rtecsNumber' : TU4056000

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold

SDS
Documenti

Documenti

Product Certifications

RUO – Research Use Only

Titolo del prodotto
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