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Invitrogen™ ELOVL7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA520913
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Descrizione
A suggested positive control is human liver tissue lysate. PA5-20913 can be used with blocking peptide PEP-1027.
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
Specifica
| ELOVL7 | |
| Polyclonal | |
| Unconjugated | |
| ELOVL7 | |
| 3-keto acyl-CoA synthase Elovl7; 9130013K24Rik; AI840082; elongation of very long chain fatty acids protein 7; elongation of very long chain fatty acids-like 7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; ELOVL family member 7, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 7; ELOVL7; Very long chain 3-ketoacyl-CoA synthase 7; very long chain 3-oxoacyl-CoA synthase 7; very-long-chain 3-oxoacyl-CoA synthase 7 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 74559, 79993 | |
| Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| A1L3X0, Q9D2Y9 | |
| ELOVL7 | |
| A 15 amino acid peptide near the amino terminus of human ELOVL7. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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